Tumor heterogeneity & clonal research
Do genetic subclones correspond to different selected surface-protein states? Data: single-cell targeted DNA plus selected surface proteins. Entry point: D100.
View tumor heterogeneity researchRESEARCH APPLICATIONS
Turn research questions into measurable differences.
Genetic variation, cell states, tissue location and individual microbes offer distinct views of living systems. A well-chosen measurement connects the research question to a result that can be interpreted.
FOUR RESEARCH DIRECTIONS
Start from the research question.
Cell states, immunity & regulation
How do expression states and chromatin accessibility differ between cell populations? Data: single-cell expression, with chromatin accessibility through a selected workflow. Entry point: R100.
View cell-state researchTissue context & microenvironments
Where are molecular signals located in tissue, and how do regions differ? Data: spatial expression plus tissue images. Entry point: Spatial.
View tissue-context researchIndividual microbes & communities
How do individual genetic differences make up population heterogeneity? Data: single-microbe genomic information. Entry point: X1000.
View single-microbe researchRESEARCH DESIGN
Three foundations of study design.
Biological unit
Single cells, tissue regions and individual microbes are different biological units. Each measurement should serve a defined question.
Samples & comparisons
Sample preparation, experimental conditions, collection time and biological replicates shape which differences can be meaningfully compared.
Interpretation & validation
Measurements provide evidence to investigate. Conclusions also require quality assessment, statistical analysis and validation appropriate to the question.
START A CONVERSATION
Explore services or discuss an experimental plan.
Start with your aims and sample context. Together, we can define the measurements, experimental path and analytical priorities.