RNA & CHROMATIN
R100
Study expression and chromatin to explore cell composition, states and regulatory clues.
Explore R100ZYENRA · SINGLE-CELL DNA & MULTIOMICS
From cellular differencesto biological insight.
Centered on single-cell DNA, ZYENRA tools connect genetic variation with selected surface protein signals for research into cellular heterogeneity and disease mechanisms.
D100Single-cell DNA + protein research platform
Understand cells. Advance our understanding of disease.
View all platformsWHY THE SAME CELL MATTERS
One cellular origin.
Two molecular perspectives.
Which variants occur in the same cell? How do selected surface-protein signals differ between clones? Each cell receives a unique origin tag in its droplet; DNA and protein reads both carry it, so analysis can assign them back to the same cell.
Explore tumor heterogeneity researchSelect a conceptual cellEach cell carries its own origin tag
DNATargeted DNA informationOrigin tagTarget regionVariantCell-of-origin tag ABC
ProteinSelected surface proteinsOrigin tagAntibody tag sequenceCell-of-origin tag ABC
Cell A selected: DNA and protein reads carry the same cell-of-origin tag A, so analysis assigns both to one cell.
Schematic
COMPLEMENTARY PERSPECTIVES
From cell states to tissues and microbes.
SINGLE-MICROBE
X1000
Investigate genomic differences within a population, one microbe at a time.
Explore X1000
SPATIAL CONTEXT
Spatial
Spatial barcode chips and workflows place molecular information in tissue context.
- Tissue location
- Spatial coordinates
- Molecular information
TWO WAYS TO START
Equip your lab.
Or plan a service project.
Run experiments in your lab
Explore instruments, reagents and assay content, then discuss a configuration and workflow for your lab.
Instruments & workflows
Choose a platform around the biological question.
Assay reagents
Define assay stages and compatible components.
Targeted content and analysis
Define target regions, protein markers and the analysis plan.
Work with our research services
Start with your aims and sample context to define the assay, quality requirements and agreed analytical deliverables.
Single-cell DNA & multimodalRNA & chromatinSpatial omicsBulk omics & custom projects
Explore services Browse panels · Partner labs wanted RESEARCH APPLICATIONS
Find your research question.
01020304
Tumor heterogeneity & clones
Variant co-occurrence, clonal composition and selected surface-protein states.
Cell states, immunity & regulation
Expression states, cell populations and chromatin accessibility.
Tissue context & microenvironments
Relationships between regional expression and tissue location.
Individual microbes & communities
Individual genomic differences and population heterogeneity.
OUR PURPOSE
Technology should gobeyond understanding,toward helping.
We hope more patients can benefit from scientific progress. Respect for data and life, responsible operations and long-term commitment guide our work.
Our purpose & principlesLET'S CONNECT
Take your research plan
to the next step.
Whether it begins with one experiment or a long-term collaboration, we welcome researchers and partners who want to move meaningful questions forward together.
Contact ZYENRA